Injectafer is approved to treat iron deficiency anemia (IDA). Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Venofer is used to treat iron deficiency anemia in people with kidney disease. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Back pain. Heart failure: Could a low sodium diet sometimes do more harm than good? This survey is being conducted by the WebMD marketing sciences department. <> Its possible that after getting two doses of Injectafer, your anemia may go away completely. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Iron infusion side effects vary depending on which form is being used. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. With anemia, you have a low level of red blood cells (RBCs) in your body. Theyll do this by checking certain blood tests. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. These effects typically last between 7 and 11 hours. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Canada residents can call a provincial poison control center. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Is the ketogenic diet right for autoimmune conditions? Yes, in some cases it may. Generics tend to cost less than brand-name drugs. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Renal elimination is negligible. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. (A generic drug is an exact copy of the active drug in a brand-name medication.) The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Injectafer helps to treat IDA by providing an iron infusion directly into your body. This medication passes into breast milk. Tell your doctor about the allergy and what signs you had. Understanding what thoseside effectsare can lead to a strategy to prevent them. Weight changes may be due to symptoms of anemia improving. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Answer by DrLact: About Venofer usage in lactation. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. This is why family members often have the same issues with drugs as others in theirfamily. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Last updated August 20, 2020. Serious side effects should be reported to a physician and/or PharmD for medical advice. In the second group, some people switched from taking iron by mouth to taking Injectafer. Side effectsare uncomfortable reactions to medications or drugs. Back pain. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. So we cant say for sure whether the drug is safe to use while youre pregnant. Learn about uses, cost, how it works, and more. This information should not be used to decide whether or not to take Venofer or any other medicine. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Consult your pharmacist or local waste disposal company. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. I actually was constipated after my 3rd but didn't think anything of it. Evenbirth controlcan lead to severeside effectslike bloodclots. Venofer may reduce the absorption of iron preparations taken by mouth. You may report side effects to the FDA at 1-800-332-1088. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. reese0809 1 yr. ago. I had Venofer infusions, 2 rounds now in the span of three years. Hemoglobin is a protein thats found inside your red blood cells. Its not known whether its safe to breastfeed while youre taking Injectafer. Innovators Monograph If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. (And Injectafer is used to treat IDA.) You may also report side effects at https://www.fda.gov/medwatch. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. What is Venofer? This includes your doctors, nurses, pharmacists, and dentists. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. The following information describes dosages that are commonly used or recommended. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Vomiting. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or pain in the arms or legs. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Copyright 1996-2023 Cerner Multum, Inc. The following information is provided for clinicians and other healthcare professionals. You may report side effects to Health Canada at 1-866-234-2345. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Medically reviewed by Sanjai Sinha, MD. There are currently no generic forms of either drug. As with most drugs, some people can have an allergic reaction after taking Injectafer. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Use of the term female in this article refers to sex assigned at birth. (Hemoglobin is a protein thats found in your red blood cells.). Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. If you notice other effects not listed above, contact your doctor or pharmacist. Most people will metabolize medication by half every time it circulates the body. Venofer is not for treating other forms of anemia not caused by iron deficiency. Learn how to store and discard medical supplies safely. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. If these effects continue or worsen, tell your doctor. Your healthcare provider will watch you closely for 30 minutes after each dose. generalized weakness. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Some products that may interact with this drug include: vitamin products, other iron-containing products. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Its responsible for carrying oxygen throughout your body. 2023 Medicine.com All rights reserved. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Then the study was split into the following two groups, which are discussed below. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. No, Injectafer itself wont make you gain weight. We comply with the HONcode standard for trustworthy health information. other treatments you receive, you will need to go back for several treatments with Venofer. Here we look at how Injectafer and Feraheme are alike and different. The oral form of the drug, called sucroferric oxyhydroxide and used . Most of these side effects may go away within a few days or a couple of weeks. Cancer patients who have anemia and are taking an ESA. Other drugs are available that can treat iron deficiency anemia (IDA). On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Side effects are uncomfortable reactions to medications or drugs. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Does Venofer Vial interact with other medications? Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Headache. % Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Pain, swelling, or redness at the injection site may occur. Its not known how common delayed allergic reaction might be in other people using Injectafer. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Terminal half-life ranges from 7 to 12 hours. (A class of medications describes a group of drugs that work in the same way.). There are different types of anemia, but IDA is the most common type. Theyll likely have you stop taking the pills while youre using Injectafer. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. We cancelled my 5th because of the reaction. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). cough. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). (See also Notes section.). But so far I feel better than before the infusion. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Mild side effects of Injectafer can include:*. And this can lead to anemia, including IDA. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Depending on your anemia symptoms, your weight changes may be different than those described here. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Call your doctor for medical advice about side effects. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Iron infusion benefits. Its given by either intravenous (IV) infusion or slow IV injection. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. . People with IDA have low blood levels of hemoglobin. Dizziness. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Here we look at how Injectafer and Venofer are alike and different. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 1 0 obj Follow all instructions closely. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Upset stomach or throwing up. Iron sucrose can also be mixed in a. With slow IV injection, the drug is given as a single, slow injection into your vein. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. taste impairment. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells.
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